Glossary May 29, 2005 by best-medical-schools · Published May 29, 2005 · Last modified May 29, 2024 What does BYE stand for? 1. Goodbye (BYE) Goodbye (BYE) is the most common and well-known meaning of the acronym. It is used as a parting salutation or farewell when leaving or ending a conversation, meeting, or gathering. The...